--- title: Cold Storage Solutions for Hazardous Drug Rooms description: USP General Chapter <800> states refrigerated antineoplastic hazardous drugs (HDs) must be stored in a dedicated refrigerator in a negative pressure area. image: https://blog.helmerinc.com/hubfs/social-suggested-images/cdn2.hubspot.nethubfs1862406social-suggested-imagesUSP%20800%20Compliance.png --- [![Helmer](https://blog.helmerinc.com/hs-fs/hubfs/HelmerScientific_September2019%20Theme/Images/helmer_logo.png?width=222&height=59&name=helmer_logo.png)](https://www.helmerinc.com/) - [Helmer Store](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Adisposables&search%5B1%5D=product_category%3Aparts_and_accessories) - [Help Center](https://www.helmerinc.com/knowledge-center) - [Blog](https://blog.helmerinc.com/) - [Manuals](https://www.helmerinc.com/manuals) - [Distributor Resources](https://www.helmerinc.com/distributor-resources) - [Contact Us](https://www.helmerinc.com/contact-us) - [Request Quote](https://www.helmerinc.com/quote-request) - [Products](https://www.helmerinc.com/helmer-products) - - [Refrigerators](https://www.helmerinc.com/) - [Pharmacy Refrigerators](https://www.helmerinc.com/product-types/pharmacy-refrigerators) - [Vaccine Refrigerators](https://www.helmerinc.com/vaccine-refrigerators) - [Blood Bank Refrigerators](https://www.helmerinc.com/product-types/blood-bank-refrigerators) - [Laboratory Refrigerators](https://www.helmerinc.com/product-types/laboratory-refrigerators) - [Freezers](https://www.helmerinc.com/) - [Vaccine Freezers](https://www.helmerinc.com/vaccine-refrigerators) - [Plasma Freezers](https://www.helmerinc.com/product-types/plasma-freezers) - [Laboratory Freezers](https://www.helmerinc.com/product-types/laboratory-freezers-30degc) - [Ultra-Low Freezers](https://www.helmerinc.com/product-types/ultra-low-temperature-freezers-80degc) - [Blood Bank](https://www.helmerinc.com/) - [Platelet Storage](https://www.helmerinc.com/product-types/platelet-storage-systems) - [Plasma Thawers](https://www.helmerinc.com/product-types/plasma-thawers) - [Cell Washer](https://www.helmerinc.com/product-types/cell-washer) - [Centrifuges](https://www.helmerinc.com/product-types/centrifuges) - [More](https://www.helmerinc.com/) - [Service Plans](https://www.helmerinc.com/custom-service-partnerships) - [GX Solutions](https://www.helmerinc.com/gx-solutions) - [Vaccine Storage](https://www.helmerinc.com/pharmacy-vaccine-refrigerators-freezers) - [Parts & Accessories](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Adisposables&search%5B1%5D=product_category%3Aparts_and_accessories) - [Custom Products](https://www.helmerinc.com/custom-products) - [All Products](https://www.helmerinc.com/helmer-products) - [Applications](https://www.helmerinc.com/) - - [For Blood Bank](https://www.helmerinc.com/search?search%5B0%5D=apps%3A206&search%5B1%5D=apps%3A211) - [Blood Bank | Transfusion Service](https://www.helmerinc.com/applications/blood-bank-transfusion-service) - [Blood Center](https://www.helmerinc.com/applications/blood-center) - [For Laboratory](https://www.helmerinc.com/search?search%5B0%5D=apps%3A201&search%5B1%5D=apps%3A216&search%5B2%5D=apps%3A221) - [Clinical Laboratory](https://www.helmerinc.com/applications/clinical-laboratory) - [Physician's Office](https://www.helmerinc.com/applications/physician-office) - [Tissue Storage](https://www.helmerinc.com/applications/tissue-storage) - [For Pharmacy](https://www.helmerinc.com/search?search%5B0%5D=apps%3A161&search%5B1%5D=apps%3A166&search%5B2%5D=apps%3A171&search%5B3%5D=apps%3A176) - [Hospital Pharmacy](https://www.helmerinc.com/applications/hospital-pharmacy) - [Specialty Pharmacy](https://www.helmerinc.com/applications/specialty-pharmacy) - [Outpatient Care](https://www.helmerinc.com/applications/outpatient-care) - [Patient Care Areas](https://www.helmerinc.com/applications/patient-care-areas) - [Retail Pharmacy](https://www.helmerinc.com/applications/retail-pharmacy) - [For Life Sciences](https://www.helmerinc.com/search?search%5B0%5D=apps%3A181&search%5B1%5D=apps%3A186&search%5B2%5D=apps%3A191&search%5B3%5D=apps%3A196) - [Biopharma & Biotech](https://www.helmerinc.com/applications/biopharma-biotech) - [Biorepository](https://www.helmerinc.com/applications/biorepository) - [Industrial](https://www.helmerinc.com/applications/industrial) - [University & Goverment](https://www.helmerinc.com/applications/university-government) - [Support](https://www.helmerinc.com/) - [Get a Quote](https://www.helmerinc.com/quote-request) - [Knowledge Center](https://www.helmerinc.com/knowledge-center) - [Technical Support](https://www.helmerinc.com/technical-support) - [Supplier Resources](https://www.helmerinc.com/supplier-resources) - [Regulatory & Compliance](https://www.helmerinc.com/regulatory-compliance) - [Distributor Locator](https://www.helmerinc.com/distributor-locator) - [Manuals](https://www.helmerinc.com/manuals) - [Helmer Store](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Aparts_and_accessories) - [Company](https://www.helmerinc.com/about-us) - [About Us](https://www.helmerinc.com/about-us) - [Contact](https://www.helmerinc.com/contact-us) - [Blog](https://blog.helmerinc.com/) - [Careers](https://www.helmerinc.com/careers) - [Tradeshows](https://www.helmerinc.com/tradeshow-schedule) - [Responsibility](https://www.helmerinc.com/) - [Generosity](https://www.helmerinc.com/making-impact) - [Safety & Wellness](https://www.helmerinc.com/safety-and-wellness) - [Sustainability](https://www.helmerinc.com/sustainability) - - ## Recent Viewed Product [![Helmer Cold Storage Image](https://blog.helmerinc.com/hs-fs/hubfs/HelmerScientific_September2019%20Theme/Images/ilr245-c.png?width=75&height=100&name=ilr245-c.png) i.Series® Double Door Laboratory Refrigerator](https://www.helmerinc.com/products/iseriesr-double-door-laboratory-refrigerator-ilr245) - [Products](https://www.helmerinc.com/helmer-products) - [Refrigerators](https://www.helmerinc.com/) - [Pharmacy Refrigerators](https://www.helmerinc.com/product-types/pharmacy-refrigerators) - [Blood Bank Refrigerators](https://www.helmerinc.com/product-types/blood-bank-refrigerators) - [Laboratory Refrigerators](https://www.helmerinc.com/product-types/laboratory-refrigerators) - [Freezers](https://www.helmerinc.com/) - [Vaccine Freezers](https://www.helmerinc.com/vaccine-refrigerators) - [Plasma Freezers](https://www.helmerinc.com/product-types/plasma-freezers) - [Laboratory Freezers](https://www.helmerinc.com/product-types/laboratory-freezers-30degc) - [ULT Freezers](https://www.helmerinc.com/product-types/ultra-low-freezers-80degc) - [Blood Bank](https://www.helmerinc.com/) - [Platelet Storage](https://www.helmerinc.com/product-types/platelet-storage-systems) - [Plasma Thawers](https://www.helmerinc.com/product-types/plasma-thawers) - [Cell Washer](https://www.helmerinc.com/product-types/cell-washer) - [Centrifuges](https://www.helmerinc.com/product-types/centrifuges) - [Other](https://www.helmerinc.com/) - [Parts & Accessories](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Adisposables&search%5B1%5D=product_category%3Aparts_and_accessories) - [Custom Products](https://www.helmerinc.com/custom-products) - [All Products](https://www.helmerinc.com/helmer-products) - [Applications](https://www.helmerinc.com/) - [For Blood Bank](https://www.helmerinc.com/search?search%5B0%5D=apps%3A206&search%5B1%5D=apps%3A211) - [Blood Bank | Transfusion Service](https://www.helmerinc.com/applications/blood-bank-transfusion-service) - [Blood Center](https://www.helmerinc.com/applications/blood-center) - [For Laboratory](https://www.helmerinc.com/search?search%5B0%5D=apps%3A201&search%5B1%5D=apps%3A216&search%5B2%5D=apps%3A221) - [Clinical Laboratory](https://www.helmerinc.com/applications/clinical-laboratory) - [Physician's Office](https://www.helmerinc.com/applications/physician-office) - [Tissue Storage](https://www.helmerinc.com/applications/tissue-storage) - [For Pharmacy](https://www.helmerinc.com/search?search%5B0%5D=apps%3A161&search%5B1%5D=apps%3A166&search%5B2%5D=apps%3A171&search%5B3%5D=apps%3A176) - [Hospital Pharmacy](https://www.helmerinc.com/applications/hospital-pharmacy) - [Specialty Pharmacy](https://www.helmerinc.com/applications/specialty-pharmacy) - [Outpatient Care](https://www.helmerinc.com/applications/outpatient-care) - [Patient Care Areas](https://www.helmerinc.com/applications/patient-care-areas) - [Retail Pharmacy](https://www.helmerinc.com/applications/retail-pharmacy) - [For Life Sciences](https://www.helmerinc.com/search?search%5B0%5D=apps%3A181&search%5B1%5D=apps%3A186&search%5B2%5D=apps%3A191&search%5B3%5D=apps%3A196) - [Biopharma & Biotech](https://www.helmerinc.com/applications/biopharma-biotech) - [Biorepository](https://www.helmerinc.com/applications/biorepository) - [Industrial](https://www.helmerinc.com/applications/industrial) - [University & Goverment](https://www.helmerinc.com/applications/university-government) - [Support](https://www.helmerinc.com/) - [Get a Quote](https://www.helmerinc.com/quote-request) - [Knowledge Center](https://www.helmerinc.com/knowledge-center) - [Technical Support](https://www.helmerinc.com/technical-support) - [Purchasing Organizations](https://www.helmerinc.com/purchasing-organizations) - [Supplier Resources](https://www.helmerinc.com/supplier-resources) - [Regulatory & Compliance](https://www.helmerinc.com/regulatory-compliance) - [Distributor Locator](https://www.helmerinc.com/distributor-locator) - [Helmer Store](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Aparts_and_accessories) - [Company](https://www.helmerinc.com/about-us) - [About Us](https://www.helmerinc.com/about-us) - [Contact](https://www.helmerinc.com/contact-us) - [Blog](https://blog.helmerinc.com/) - [Careers](https://www.helmerinc.com/careers) - [Tradeshows](https://www.helmerinc.com/tradeshow-schedule) - [Responsibility](https://www.helmerinc.com/) - [Generosity](https://www.helmerinc.com/making-impact) - [Safety & Wellness](https://www.helmerinc.com/safety-and-wellness) - [Sustainability](https://www.helmerinc.com/sustainability) - [Store](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Adisposables&search%5B1%5D=product_category%3Aparts_and_accessories) - [Help Center](https://www.helmerinc.com/knowledge-center) - [Blog](https://blog.helmerinc.com/) - [Manuals](https://www.helmerinc.com/manuals) - [Distributor Resources](https://www.helmerinc.com/distributor-resources) - [Contact Us](https://www.helmerinc.com/contact-us) - [Request Quote](https://www.helmerinc.com/quote-request) Keyword Keyword [View All](https://blog.helmerinc.com/) - [Pharmacy (296)](https://blog.helmerinc.com/topic/pharmacy) - [Clinical Laboratory (263)](https://blog.helmerinc.com/topic/clinical-laboratory) - [Blood Bank (237)](https://blog.helmerinc.com/topic/blood-bank) - [Vaccine Storage (216)](https://blog.helmerinc.com/topic/vaccine-storage) - [News & Events (74)](https://blog.helmerinc.com/topic/news-events) - [Helmer Generosity (54)](https://blog.helmerinc.com/topic/helmer-generosity) - [Life Science Research (48)](https://blog.helmerinc.com/topic/life-science-research) - [Service (27)](https://blog.helmerinc.com/topic/service) ### Subscribe to Our Newsletter --- ##### [Shop Now](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Adisposables&search%5B1%5D=product_category%3Aparts_and_accessories) - [**Blue**View](https://blog.helmerinc.com) - Cold Storage Solutions for Hazardous Drug Rooms # Cold Storage Solutions for Hazardous Drug Rooms Posted on Jul 15, 2021 by Kristen Yawit [![cdn2.hubspot.nethubfs1862406social-suggested-imagesUSP 800 Compliance](https://blog.helmerinc.com/hs-fs/hubfs/social-suggested-images/cdn2.hubspot.nethubfs1862406social-suggested-imagesUSP%20800%20Compliance.png?width=602&name=cdn2.hubspot.nethubfs1862406social-suggested-imagesUSP%20800%20Compliance.png)](https://www.helmerinc.com/gx-solutions) When it comes to determining what refrigerators are safe and effective for use in your hazardous drug clean room, it is important to follow the guidelines set forth by the United States Pharmacopeia (USP). As stated in USP General Chapter <800>, refrigerated antineoplastic hazardous drugs (HDs) must be stored in a dedicated refrigerator in a negative pressure area with at least 12 air changes per hour (ACPH). If the refrigerator is placed in a negative pressure buffer room, an exhaust located adjacent to the refrigerator’s compressor and behind the refrigerator should be considered to help sweep out any particles. Helmer refrigerators do not release any additional particles into the environment, however, the hazardous products stored inside the refrigerator may. Ensure the refrigerator storing your antineoplastic HDs provides optimal temperature uniformity, stability, and recovery. This keeps your valuable pharmaceuticals stored at precise temperatures to ensure efficacy and safety. Pharmaceutical-grade refrigerators will have a uniformity spec of +/-1 degree C°. Do not use a refrigerator pass-thru in your HD clean room. This is specific to negative pressure rooms. Other methods of containment should be used for transferring product in and out of the HD clean room. Positive pressure clean rooms may continue using pass-thru refrigerators to enhance clean room workflows and reduce foot traffic in and out of the clean room, therefore, reducing contamination risk. This infographic highlights the most important information relating to your USP <800> refrigerator. [![Infographic understanding USP <800>](https://blog.helmerinc.com/hs-fs/hubfs/Content/Infographics/USP%20_800_%20%20Infographic.png?width=800&name=USP%20_800_%20%20Infographic.png)](https://blog.helmerinc.com/usp-800-refrigerator) ##### **OTHER BLOGS YOU MIGHT BE INTERESTED IN...** - [Complying with USP 800: Refrigerators in Your Negative Pressure Hazardous Drug Room](https://blog.helmerinc.com/complying-with-usp-800-refrigerators) - [Rate of USP <797> & USP <800> Compliance](https://blog.helmerinc.com/usp-797-usp-800-compliance-rates) - [USP <800> Refrigerator Frequently Asked Questions Answered](https://blog.helmerinc.com/usp-800-refrigerator) - [USP <800> Hazardous Drugs – Handling in Healthcare Settings Drives Pharmacy Renovations](https://blog.helmerinc.com/usp-800-pharmacy-renovations) Helmer Scientific’s medical-grade refrigerators are safe for the use for the storage of hazardous drugs in your clean room. If you have questions about placing a refrigerator in your clean room, download our USP <800> Refrigerator FAQ. [![Download the FAQ »](https://no-cache.hubspot.com/cta/default/1862406/be9179eb-2fdc-4f3b-abdf-a973b491db6d.png)](https://cta-redirect.hubspot.com/cta/redirect/1862406/be9179eb-2fdc-4f3b-abdf-a973b491db6d)   ![Kristen Yawit](https://blog.helmerinc.com/hubfs/Images/Head%20Shots/photo.jpg) ### Written by [Kristen Yawit](https://blog.helmerinc.com/author/kristen-yawit) With over 5 years of experience in healthcare marketing strategy and pharmacy product development and management, Kristen is the Segment Marketing Manager at Helmer Scientific, focused on the Pharmacy and Vaccine segments. #### Share or write a comment! [![Share on facebook](https://7528309.fs1.hubspotusercontent-na1.net/hub/7528309/hubfs/raw_assets/public/mV0_d-web-default-modules_hubspot/img/facebook-color.png?width=24&name=facebook-color.png)](http://www.facebook.com/share.php?u=https%3A%2F%2Fblog.helmerinc.com%2Fcold-storage-hazardous-drug-rooms%3Futm_medium%3Dsocial%26utm_source%3Dfacebook) [![Share on linkedin](https://7528302.fs1.hubspotusercontent-na1.net/hub/7528302/hubfs/raw_assets/public/mV0_d-web-default-modules_hubspot/img/linkedin-color.png?width=24&name=linkedin-color.png)](http://www.linkedin.com/shareArticle?mini=true&url=https%3A%2F%2Fblog.helmerinc.com%2Fcold-storage-hazardous-drug-rooms%3Futm_medium%3Dsocial%26utm_source%3Dlinkedin) ### Subscribe to Our BlueView Blog ### Subscribe to Our Newsletter --- ### Recent Posts --- [![Share on facebook](https://7528309.fs1.hubspotusercontent-na1.net/hub/7528309/hubfs/raw_assets/public/mV0_d-web-default-modules_hubspot/img/facebook-color.png?width=24&name=facebook-color.png)](http://www.facebook.com/share.php?u=https%3A%2F%2Fblog.helmerinc.com%2Fcold-storage-hazardous-drug-rooms%3Futm_medium%3Dsocial%26utm_source%3Dfacebook) [![Share on linkedin](https://7528302.fs1.hubspotusercontent-na1.net/hub/7528302/hubfs/raw_assets/public/mV0_d-web-default-modules_hubspot/img/linkedin-color.png?width=24&name=linkedin-color.png)](http://www.linkedin.com/shareArticle?mini=true&url=https%3A%2F%2Fblog.helmerinc.com%2Fcold-storage-hazardous-drug-rooms%3Futm_medium%3Dsocial%26utm_source%3Dlinkedin) [![Helmer](https://blog.helmerinc.com/hubfs/HelmerScientific_September2019%20Theme/Images/helmer_logo.png)](https://www.helmerinc.com/) [About Helmer Scientific](https://www.helmerinc.com/about-us) - [Regulatory & Compliance](https://www.helmerinc.com/regulatory-compliance) - [About Us](https://www.helmerinc.com/about-us) - [Blog](https://blog.helmerinc.com/) - [Generosity](https://www.helmerinc.com/making-impact) - [Careers](https://www.helmerinc.com/careers) - [Contact Us](https://www.helmerinc.com/contact-us) [Support & Resources](https://www.helmerinc.com/knowledge-center) - [Knowledge Center](https://www.helmerinc.com/knowledge-center) - [Distributor Locator](https://www.helmerinc.com/distributor-locator) - [Distributor Resources](https://www.helmerinc.com/distributor-resources) - [Request a Quote](https://www.helmerinc.com/quote-request) - [Submit Service Request](https://www.helmerinc.com/technical-support) - [Supplier Resources](https://www.helmerinc.com/supplier-resources) - [Helmer Store](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Adisposables&search%5B1%5D=product_category%3Aparts_and_accessories) [Products](https://www.helmerinc.com/helmer-products) - [Pharmacy Refrigerators](https://www.helmerinc.com/product-types/pharmacy-refrigerators) - [Vaccine Refrigerators](https://www.helmerinc.com/vaccine-refrigerators) - [Blood Bank Refrigerators](https://www.helmerinc.com/product-types/blood-bank-refrigerators) - [Laboratory Refrigerators](https://www.helmerinc.com/product-types/laboratory-refrigerators) - [Laboratory Freezers](https://www.helmerinc.com/product-types/laboratory-freezers-30degc) - [Vaccine Freezers](https://www.helmerinc.com/pharmacy-vaccine-refrigerators-freezers) - [Plasma Freezers](https://www.helmerinc.com/product-types/plasma-freezers) - [ULT Freezers](https://www.helmerinc.com/product-types/ultra-low-freezers-80degc) - [Platelet Storage](https://www.helmerinc.com/product-types/platelet-storage-systems) - [Plasma Thawers](https://www.helmerinc.com/product-types/plasma-thawers) - [Cell Washer](https://www.helmerinc.com/product-types/cell-washer) - [Centrifuges](https://www.helmerinc.com/product-types/centrifuges) - [Custom Products](https://www.helmerinc.com/custom-products) - [Helmer Store](https://www.helmerinc.com/search?search%5B0%5D=product_category%3Adisposables&search%5B1%5D=product_category%3Aparts_and_accessories) [For Laboratory](https://www.helmerinc.com/search?search%5B0%5D=apps%3A201&search%5B1%5D=apps%3A206&search%5B2%5D=apps%3A211&search%5B3%5D=apps%3A216&search%5B4%5D=apps%3A221) - [Clinical Laboratory](https://www.helmerinc.com/applications/clinical-laboratory) - [Blood Bank | Transfusion Service](https://www.helmerinc.com/applications/blood-bank-transfusion-service) - [Blood Center](https://www.helmerinc.com/applications/blood-center) - [Physician's Office](https://www.helmerinc.com/applications/physician-office) - [Tissue Storage](https://www.helmerinc.com/applications/tissue-storage) [For Pharmacy](https://www.helmerinc.com/search?search%5B0%5D=apps%3A161&search%5B1%5D=apps%3A166&search%5B2%5D=apps%3A171&search%5B3%5D=apps%3A176) - [Hospital Pharmacy](https://www.helmerinc.com/applications/hospital-pharmacy) - [Specialty Pharmacy](https://www.helmerinc.com/applications/specialty-pharmacy) - [Outpatient Care](https://www.helmerinc.com/applications/outpatient-care) - [Patient Care Areas](https://www.helmerinc.com/applications/patient-care-areas) - [Retail Pharmacy](https://www.helmerinc.com/applications/retail-pharmacy) [For Life Sciences](https://www.helmerinc.com/search?search%5B0%5D=apps%3A181&search%5B1%5D=apps%3A186&search%5B2%5D=apps%3A191&search%5B3%5D=apps%3A196) - [BioPharma & BioTech](https://www.helmerinc.com/applications/biopharma-biotech) - [BioRepository](https://www.helmerinc.com/applications/biorepository) - [Industrial](https://www.helmerinc.com/applications/industrial) - [University & Government](https://www.helmerinc.com/applications/university-government) Copyright 2024 Helmer Scientific Inc. - [Terms of Use](https://www.helmerinc.com/terms-use) - [Privacy Policy](https://www.helmerinc.com/privacy-policy) - [Sales Terms & Conditions](https://www.helmerinc.com/sales-terms-conditions) - [Contact Us](https://www.helmerinc.com/contact-us) - [800-743-5637](tel:8007435637) ```json { "@context" : "https://schema.org", "@type" : "BlogPosting", "author" : { "@type" : "Person", "name" : "Kristen Yawit", "url" : "https://blog.helmerinc.com/author/kristen-yawit" }, "dateModified" : "2021-07-15T13:00:01.164Z", "datePublished" : "2021-07-15T13:00:00.000Z", "headline" : "Cold Storage Solutions for Hazardous Drug Rooms", "image" : [ "https://blog.helmerinc.com/hubfs/social-suggested-images/cdn2.hubspot.nethubfs1862406social-suggested-imagesUSP%20800%20Compliance.png" ], "mainEntityOfPage" : { "@id" : "https://blog.helmerinc.com/cold-storage-hazardous-drug-rooms", "@type" : "WebPage" }, "publisher" : { "@type" : "Organization", "logo" : { "@type" : "ImageObject", "url" : "https://blog.helmerinc.com/hubfs/logo.png" }, "name" : "Helmer Scientific" } } ```